最新发表文章：
Leilei Shi, Qinghua Guan, Xihui Gao, Xin Jin, Li Xu, Jian Shen*, Chenwei Wu, Xinyuan Zhu, and Chuan Zhang*, “Reaction Based Color-Convertible Fluorescent Probe for Ferroptosis Identification”, Analytical Chemistry, 2018, in press.
Chenwei Wu, Li Xu, Leilei Shi, Xihui Gao, Jing Li, Xinyuan Zhu*, Chuan Zhang*, “Supramolecularly self-assembled nano-twin drug to reverse the multidrug resistance”, Biomaterials Science, 6, 2261-2269 (2018).
Dongbo Guo, Shuting Xu, Yu Huang, Huangyong Jiang, Wumaier Yasen, Nan Wang, Yue Su, Jiwen Qian, Jing Li, Chuan Zhang*, Xinyuan Zhu, “Platinum(IV) Complex-Based Two-in-One Polyprodrug for A Combinatorial Chemo-Photodynamic Therapy”, Biomaterials, 177，67-77 (2018).
Shuting Xu, Xinyuan Zhu, Chuan Zhang, Wei Huang, Yongfeng Zhou, Deyue Yan*, “Oxygen and Pt(II) self-generating conjugate for synergistic photo-chemo therapy of hypoxic tumor”, Nature Communications, DOI: 10.1038/s41467-018-04318-1 (2018).
Ma Y., Liu H., Mou Q., Yan D., Zhu X., Zhang C.* “Floxuridine-Containing Nucleic Acid Nanogels for Anticancer Drug Delivery”, Nanoscale, 10, 8367 – 8371 (2018).
Shi L., Gao X., Yuan W., Xu L., Deng H., Wu C., Yang J., Jin X.*, Zhang C.*, Zhu X., “Endoplasmic Reticulum Targeted Fluorescent Nanodot with Large Stokes Shift for Vesicular Transport Monitoring and Long-Term Bioimaging”, Small, DOI: 10.1002/smll.201800223 (2018).
Ding F., Mou Q., Ma Y., Pan G., Guo Y., Tong G., Choi C. H. J., Zhu X., Zhang C.*, “Crosslinked Nucleic Acid Nanogel For Effective siRNA Delivery and Antitumor Therapy”, Angew. Chem. Int. Ed., 57, 3064-3068 (2018).
Mou Q., Ma Y., Pan G., Xue B., Yan D., Zhang C.*, Zhu X.*, “DNA Trojan Horses: The Self-Assembled Floxuridine-Containing DNA Polyhedra for Cancer Therapy”, Angew. Chem. Int. Ed., 56, 12528–12532 (2017)
Wang D., Liu B., Ma Y., Wu C., Mou Q., Deng H., Wang R., Yan D., Zhang C.*, Zhu X.*, “A molecular recognition approach to synthesize nucleoside analogue based multifunctional nanoparticles for targeted cancer therapy”, J. Am. Chem. Soc., 139, 14021-14024 (2017)
科研成果转化：
本课题组在高分子材料合成、改性和应用方面具有多年研发经验，与国内外知名企业开展长期而深入的产学研合作，研究领域涉及高分子材料合成与改性、聚合物加工助剂、超支化聚合物胶黏剂、新型涂料、纳米药物、生物检测等。课题组目前全职产业化教师和博士后研究人员等10余人；申请各类横向课题40余项，累计获得资助经费9000余万元；已经申请了国家发明专利60余项，其中授权专利30余项。代表性转化项目包括：
（一）超支化聚合物流动改善剂
针对现有单体型增塑剂和聚合型增塑剂的不足，设计一类超支化聚合物型流动性改善剂，实现在大幅降低加工状态下材料粘度同时，保持其服役条件下材料综合性能，满足高分子材料加工领域高精度加工和节能降耗的市场需求。该项目合成工艺简单，无三废排放，反应温和可控，高效绿色等特点。
（二）基于超支化聚合物的新型涂料
开发了一种可紫外光固化的超支化星形聚合物涂料，该涂料具有紫外光下快速固化的能力，在线性聚合物臂聚合度适宜的情况下，超支化星形聚合物结合了超支化聚合物与线性聚合物的优点，提高了涂料的流平性、固化速率、硬度、附着力和耐性等，鉴于其良好的附着力和生物降解性，在汽车和医疗等领域具有广阔应用前景。
朱新远课题组 